News from CROI 2013

The 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) took place at the Georgia World Congress Center in Atlanta, USA, in early March 2013.

We reported on key research presented at the conference, publishing news and sending out summary bulletins by email, three during the conference week and one the following week.

CROI is a scientific conference, bringing together around 4000 researchers and doctors to share their work and debate current issues. As well as publishing abstracts and posters on the official conference website, the conference organisers film key sessions and produce webcasts, so you can watch presentations online. They aimed to make around 90% of the conference available online and we included relevant links in our news stories and bulletins.

“The coverage made me feel I was at the conference and I appreciate NAM's effort in sharing the bulletins.” NAM bulletin subscriber

aidsmap news from CROI 2013

Faldaprevir ups interferon response in HIV/HCV co-infection

Adding the hepatitis C virus (HCV) protease inhibitor faldaprevir (formerly BI 201335) to pegylated interferon and ribavirin led to a higher early response rate and the potential

Published
11 March 2013
By
Liz Highleyman
Simeprevir pushes HCV cure rate above 75% for HIV/HCV co-infection

Adding the new hepatitis C virus (HCV) protease inhibitor simeprevir (formerly TMC435) to pegylated interferon and ribavirin cures about three-quarters of HIV/HCV co-infected people, most of them with

Published
11 March 2013
By
Liz Highleyman
Contraceptive injections and HIV infection risk – a public health conundrum

The concerns about a possible increase in risk of HIV acquisition with some hormonal contraceptive methods need to be understood in the context of the

Published
10 March 2013
By
Roger Pebody
New integrase inhibitor dolutegravir helps treatment-experienced people on failing therapy

The next-generation integrase inhibitor dolutegravir proved more beneficial than raltegravir (Isentress) for treatment-experienced people with resistance to two or more antiretroviral drug classes, researchers reported in a poster

Published
10 March 2013
By
Liz Highleyman
Second-line NRTI-sparing regimen proves equally effective for resource-limited settings

A second-line antiretroviral regimen of lopinavir/ritonavir (Kaletra/Aluvia) and raltegravir (Isentress) proved just as effective as a regimen containing lopinavir/ritonavir and two or three nucleoside or nucleotide analogues

Published
07 March 2013
By
Keith Alcorn
Can people with resistant HIV omit NRTIs when switching from a failing regimen?

Omitting nucleoside reverse transcriptase inhibitors (NRTIs) when switching from a non-suppressive regimen to a new combination with at least two active agents can reduce pill burden and

Published
07 March 2013
By
Liz Highleyman
New pro-drug tenofovir alafenamide appears equally effective but better tolerated

Tenofovir alafenamide fumarate or TAF (formerly GS-7340), a new pro-drug of the widely used NRTI tenofovir, reaches cells harbouring HIV more easily than the older tenofovir disoproxil

Published
07 March 2013
By
Liz Highleyman
Slow progress in expansion of voluntary circumcision coverage

Progress towards greater coverage of voluntary male circumcision (MC) in Africa remains slow, and is due as much to men’s fear of the operation as it is

Published
07 March 2013
By
Gus Cairns
Dosing of key TB drug rifampicin could go higher

Rifampicin, a key drug in tuberculosis (TB) treatment, can be tolerated at much higher doses than used in current clinical practice – suggesting that much higher drug

Published
07 March 2013
By
Keith Alcorn
Once-weekly continuation phase TB treatment equals standard of care

A new two-drug combination of rifapentine and moxifloxacin can allow tuberculosis (TB) treatment to be taken once-weekly during the four-month continuation phase, Dr Amina Jindani of St

Published
07 March 2013
By
Keith Alcorn
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  • Can people with drug-resistant #HIV omit NRTIs when switching from a failing regimen? http://dlvr.it/334k1m #CROI #CROI201307 Mar 2013 04:48
  • Here's the third of our #CROI bulletins. Among other things, news on #HIV, #TB and #HBV: http://bit.ly/WwG6OD #CROI201307 Mar 2013 03:25
  • Currently at #CROI2013 with poster. Thanks to all for participation and support.07 Mar 2013 12:48
  • Dually active antiretroviral therapy protects against hepatitis B infection #aids #hiv #hepB http://www.aidsmap.com/page/2590079/07 Mar 2013 06:40
  • Watching #CROI presentations, eating vegan pesto, and loving life #publichealth #nerd07 Mar 2013 03:55
  • I survived #CROI2013. Adding to the list of things that this former AIDS baby has done before turning 30. #thankyouscience #byebyegp12007 Mar 2013 01:11
  • A take home from #croi - rush for DAA now or wait for IFN-free therapy? Fibrosis assessment in #HIV #hepC co-infection crucial for decision.07 Mar 2013 12:38
  • One of the best presentations at #CROI2013. Beyrer on the global HIV in MSM epidemic http://webcasts.retroconference.org/console/player/19422?mediaType=audio07 Mar 2013 12:16
  • Behind the Miracle Cure a Broken System Lurks from @HIVPrevJustice http://rmdy.hm/iJu #hiv #aids #croi2013 #policy #healthcare06 Mar 2013 11:01
  • Alexander Pym - last lecture of #CROI- talking about how to make effective XDR treatment #worldTBday - watch it at http://retroconference.org06 Mar 2013 10:58
  • Alexander Pym #CROI asks are we over treating for MDRTB???06 Mar 2013 10:47
  • Soumya Swaminthan at #CROI2013 excellent presentation on TB in children and women,in children.06 Mar 2013 10:37
  • #CROI Exciting research into point of care viral load testing and early infant diagnosis. @Jhpiego @mchipnet06 Mar 2013 10:04
  • At #CROI conference center, these carts are EVERYWHERE. With 8 hrs of presentations a day, they know what we need. http://pic.twitter.com/fs25Sy3kFA06 Mar 2013 07:18
  • Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation http://dlvr.it/32qdKt #CROI06 Mar 2013 03:57
  • If like me you didn't make it to Atlanta - this is pretty neat: http://webcasts.retroconference.org/ #CROI06 Mar 2013 03:55
  • I've seen several intriguing posters at #CROI that deserve more attention than they usually get (there's so many)! Hard to sum in 140 chars.06 Mar 2013 04:21
  • Slight increase in transmitted drug resistance in the US. Especially for NNRTIs #CROI201306 Mar 2013 03:59
  • Worrying pattern seen elsewhere too MT @aidsmap_news: Black MSM run higher risk of HIV despite fewer partners http://dlvr.it/32nZgz #CROI”06 Mar 2013 03:17
  • next lecture- substantial burden of non-AIDS cancers in PLHIV, from Pune India - Sheela Godbole #CROI06 Mar 2013 03:10
  • The second of our news summary bulletins from #CROI is now available online: http://bit.ly/WuGRYh #CROI2013 #HIV #HCV06 Mar 2013 02:45
  • Plenary this morning on attempting to cure HIV with gene modified stem cell transplants. #CROI201306 Mar 2013 02:32
  • from magic mountain to table mountain lecture just ended, sobering #CROI #worldTBday #tuberculosis video will be on http://retroconference.org06 Mar 2013 02:00
  • A.Diacon @ #CROI 2013: "Participants of MDR drug clinical trial need to be followed up up to 1 y following completion of study"06 Mar 2013 01:49
  • Black gay men run higher risk of HIV infection despite fewer partners http://dlvr.it/32nZgz #CROI06 Mar 2013 01:19
  • RT @DrFriedenCDC: CDC at #CROI: #HIV-infected adults with healthcare coverage are more likely to have their virus under control. http://go.usa.gov/22CA06 Mar 2013 12:52
  • Dual CCR5/CCR2 inhibitor cenicriviroc has anti-inflammatory as well as anti-HIV effect http://dlvr.it/32l1vp #CROI #CROI2013 #HIV06 Mar 2013 10:27
  • New NNRTI MK-1439 shows promise in early clinical trial http://dlvr.it/32l1zC #CROI06 Mar 2013 10:03
  • Today is a full #TB day at #CROI 2013 including a plenary talk, oral abstracts, poster sessions and a symposium.06 Mar 2013 09:06
  • Small risk of neurological birth defects due to efavirenz confirmed in French cohort http://dlvr.it/32hM9r #CROI06 Mar 2013 05:20
  • There was a good and necessary discussion today at #CROI2013 about making sure HIV sequence data is untraceable back to people.06 Mar 2013 05:00
  • HIV treatment for children is safe and highly effective without laboratory monitoring in large African trial http://dlvr.it/32gsR2 #CROI06 Mar 2013 04:15
  • #CROI video and slides -- Tuesday, 3/05/2013 -- http://bit.ly/W3TdnT06 Mar 2013 03:12
  • New interview with @whitehouse Office of Natl AIDS Policy Director Dr. Colfax discussing HIV research at #CROI: http://go.usa.gov/2bc306 Mar 2013 01:09
  • no magic bullet - building HIV prevention response for young women requires multiple levels of intervention - Sinead Delany-Moretilwe #CROI05 Mar 2013 10:16
  • The #CROI #HIV restriction factor discussion on TRIM5alpha has gotten quite feisty!05 Mar 2013 10:09
  • Gary Harper re: HIV behav & biomed synergy: "You can make the best HIV pill, but if I don't put it in my mouth, it won't work." #CROI201305 Mar 2013 09:52
  • Brilliant, beautiful plenary by Chris Beyrer on global #HIV epidemic in gay/bisex/otherMSM #CROI #CROI2013 Watch at http://bit.ly/WB8j1q05 Mar 2013 09:18
  • MSF at #CROI: "Viral load monitoring is still 1 of the best tools we have to stay one step ahead of the virus” http://ow.ly/ioazW #HIV05 Mar 2013 08:55
  • Great session on HIV, contraception and fertility intentions at #CROI @Jhpiego @mchipnet @AnnePfitzer05 Mar 2013 07:20
  • Julio Montaner at #CROI 'it's more than just money that keeps people from accessing care' #sdoh05 Mar 2013 07:12
  • exome sequencing of elite and rapid HIV progressors, results form the exploratory pilot of the UK HIV Genomics consortium #CROI @EricTopol05 Mar 2013 07:11
  • In 20 city CDC study, gay/bisexual men w/ HIV who were already aware of their infection increased from 56% in 2008 to 66% in 2011. #CROI05 Mar 2013 05:57
  • CDC at #CROI: #HIV prevalence in gay/bisexual men in 20 cities remained steady at <20% from 2008 to 201105 Mar 2013 05:39
  • Today's #CROI bulletin is now available in English, French, Spanish, Portuguese and Italian on our #CROI2013 pages: http://www.aidsmap.com/croi201305 Mar 2013 05:51
  • Cenicriviroc data looks nice -- lowers LDL too, daily dosing #CROI05 Mar 2013 05:13
  • #CROI ARROW trial reports benefit of cotrimoxazole for HIV+ kids even when on ART--less malaria, fewer hospitalizations @Jhpiego @mchipnet05 Mar 2013 04:37
  • We're watching out for new developments getting unveiled at #croi2013, some interesting breakthroughs being announced05 Mar 2013 04:34
  • Bulletin électronique en français sur les nouvelles de #CROI2013: http://bit.ly/VA3YiW #VIH #CROI05 Mar 2013 04:08
  • Black MSM are disproportionately affected by HIV and less aware of their status. GET TESTED #CROI201305 Mar 2013 03:40

NAM is partnering with gTt (Barcelona), GAT (Lisbon) and LILA (Como) to deliver the CROI 2013 bulletins, which have also been made possible thanks to support from Bristol-Myers Squibb. NAM’s wider conference news reporting services have been supported by Abbott, Boehringer Ingelheim, Janssen, Roche and ViiV Healthcare. The funders have no editorial control over the content of the materials.